A new study has shown the effects of the antihypertensive drug calcium channel blocker (CCB) Norvasc have on the cardiovascular system in patients with coronary artery disease (CAD). This study, in a large, open-label, randomized, placebo-controlled trial, was conducted to determine the effect of CCB on the cardiovascular system in patients with CAD. Patients with CAD were assigned to receive a CCB of either 0.9 or 1.0 mg once daily for 8 weeks.
A total of 40 CAD patients with moderate or severe CAD (≥3.0 or <3.5% stenosis) were studied. All patients were followed for a minimum of 9 months. During this period, a total of 1,521 CAD patients were randomized to receive CCB or placebo.
The primary endpoint was the change in mean blood pressure (BP) (mm Hg systolic and diastolic BP) in the CAD group (0.9 mg/ml, <0.9 mg/ml). This difference was significant between the CCB and placebo groups for all time points. At week 8, a mean increase in mean BP in the CCB group was 4.8 mm Hg systolic (p < 0.001) and 0.2 mm Hg diastolic (p < 0.01), and at week 24, a mean increase in mean BP in the CCB group was 9.6 mm Hg systolic (p < 0.001) and 0.1 mm Hg diastolic (p < 0.01), but there was no difference in the change in mean BP between the two groups.
The second primary endpoint was the change in mean blood pressure (BP) (mm Hg systolic and diastolic BP) in the CAD group (0.9 mg/ml, <0.9 mg/ml). At week 8, a decrease in mean BP in the CCB group was 9.3 mm Hg systolic (p < 0.01), and at week 24, a decrease in mean BP in the CCB group was 13.2 mm Hg systolic (p < 0.001). At week 8, a mean increase in mean BP in the CCB group was 3.6 mm Hg systolic (p < 0.01), and a mean increase in mean BP in the CCB group was 4.5 mm Hg systolic (p < 0.001) but there was no difference in the change in mean BP between the two groups.
The study was stopped early after patients reported a reduction in their mean BP (from 0.9 mg to 0.9 mg/ml) and mean BP systolic (from 0.2 to 0.1 mm Hg) at week 8.
The results of the study are presented in.
A total of 40 CAD patients were randomized to receive CCB (0.9 mg/ml, <0.9 mg/ml) or placebo (0.9 mg/ml).The primary endpoint was the change in mean blood pressure (BP) in the CAD group (0.9 mg/ml, <0.9 mg/ml) and the change in mean BP systolic (from 0.2 to 0.1 mm Hg) during the 8 weeks of treatment.
In the first 8 weeks of treatment, there was a mean increase in mean BP of 6.7 mm Hg systolic (p < 0.01) and a mean increase in mean BP systolic of 4.3 mm Hg systolic (p < 0.01) in the CAD group. At week 8, there was a mean increase of 4.8 mm Hg systolic (p < 0.01) and a mean increase of 5.6 mm Hg systolic (p < 0.01) in the CAD group.
Norvasc 5mg Tablet is used to treat high blood pressure in the lungs, lower blood pressure in the chest and reduce chest pain.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Norvasc Tablet may be taken with or without food, but it is better to take it at a fixed time. If you are using the powder for making the medicine, chew it whole. Do not use an overdose of it or give it to others with any problem.
Common side effects of Norvasc Tablet include:
You can buy Norvasc Tablet online from untrusted websites. If you have any queries regarding this product or its supply, please contact your local branch of online pharmacy. Our sales representatives are available to assist you in procuring it from the website of your choice.
You can also contact our sales personnel directly with any queries by using the messaging feature on our website. We strive to have a safe and confidential selling environment, thus our customers are advised to refrain from selling this product without approval from their local branch of online pharmacy.
Before taking this medicine, you must inform your doctor if you are allergic to it, or if you have any other allergies. You must also inform your doctor if you are taking any other medicines, especially those that cause drowsiness, which are prescribed for you by your doctor.
It is important to keep in mind that Norvasc Tablet is prescribed for you only. Do not take it if you are allergic to it. Norvasc Tablet is not recommended for use in children under 12 years of age. Norvasc Tablet is not recommended for use in women and children. Norvasc Tablet should not be used by people who are allergic to any of its ingredients. Before using Norvasc Tablet, you must inform your doctor about any of its ingredients.
Norvasc Tablet is not recommended for use in pregnant or breast-feeding women. Inform your doctor about the possible risks and side effects when taking this medicine while pregnant or breast-feeding.
See also Precautions section.In rare cases, Norvasc Tablet has been associated with an increased risk of certain serious side effects. Although these side effects are rare, you should report any unusual or severe symptoms or the occurrence of new or worsening symptoms to your doctor or health care provider.
If you experience any of the above-mentioned symptoms, stop using Norvasc Tablet and seek medical attention immediately as they may be symptoms of a serious allergic reaction. If you are not sure whether you are allergic to any medicine, start using a new medicine without first consulting your doctor.
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Norvasc 10mg
General Medicines (Generic)
Patients for treatment of Raynaud's syndrome (a disorder characterized by abnormal, excessive blood vessel swelling, or ulceration of the superficial tissues of the body).
The recommended dose of Norvasc (Norlimax) is 10 mg once daily. The typical adult dosage is 10 mg once daily. The recommended daily dosage for Raynaud's syndrome is 2.5 mg once daily. In patients who are not adequately responsive to oral Norvasc, or in patients with impaired renal function, a lower dosage of 5 mg once daily may be considered.
The most commonly reported adverse events reported with Norvasc are as follows:
Norvasc is not for use in patients allergic to aspirin or any other anti-inflammatory medicine, including non-steroidal anti-inflammatory drugs (NSAIDs).
The most commonly reported adverse events reported with Norvasc (Norlimax) are as follows:
Norvasc (Norlimax) is not for use in patients allergic to aspirin or any other anti-inflammatory medicine, including non-steroidal anti-inflammatory drugs (NSAIDs).
Available in 5mg, 10mg, and 20mg strength, Norvasc (Norlimax) is available in the following strengths:
This product is not intended for use by women or children. Norvasc tablets must be taken orally with water. Norvasc (Norlimax) should be swallowed whole with a glass of water. The tablets may be chewed or crushed.
Do not use if the patient has been unable to swallow or if the patient has a fever that is higher than 38ºF (15ºC).
The recommended dosage of Norvasc (Norlimax) is 10 mg once daily.
Sold and Supplied by Healthylife Pharmacy
This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.
Medicare CardNo MedicareConcession
$17.95
Healthylife provides general product information such as nutritional information, country of origin and product packaging for your convenience. This information is intended as a guide only, including because products change from time to time. Please read product labels before consuming. For therapeutic goods, always read the label and follow the directions for use on pack. If you require specific information to assist with your purchasing decision, we recommend that you contact the manufacturer via the contact details on the packaging or email us at [email protected]. Product ratings and reviews are taken from various sources including Bazaarvoice. Healthylife does not represent or warrant the accuracy of any statements, claims or opinions made in product ratings and reviews.
Healthylife Product WarningsHealthylife contains the following warnings regarding this product:
Healthylife amendable ca 5.45
Healthylife IngredientsActive Ingredients: 10 mg of Norvasc
Ingredients: Lactose Monohydrate, Xanthan Gum, Sodium Laurilsulfate, Purified Water,cience-to-stage
Product Dquartered in the United Kingdom, Healthylife operates through a global sales distribution network. This agreement allows Healthylife to maintain a consistent product portfolio, improve its product packaging and expand its globally reach.
Sold and Supplied by Healthylife Pharmacy
This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.
Medicare CardNo MedicareConcession
$18.95
Healthylife provides general product information such as nutritional information, country of origin and product packaging for your convenience. This information is intended as a guide only, including because products change from time to time. Please read product labels before consuming. For therapeutic goods, always read the label and follow the directions for use on pack. If you require specific information to assist with your purchasing decision, we recommend that you contact the manufacturer via the contact details on the packaging or email us at [email protected]. Product ratings and reviews are taken from various sources including Bazaarvoice. Healthylife does not represent or warrant the accuracy of any statements, claims or opinions made in product ratings and reviews.
Keep out of the sight and reach of childrenHealthylife products are nature-stemmed products, not drugs. Therefore, only your doctor will determine if Healthylife is a suitable product for you. Safety and effectiveness have not been established and therefore, this product must not be used by patients with a known allergy or intolerance to various other medications. Always consult with a qualified healthcare professional before taking any new prescription or over the counter medicines. |
Healthylife wholesalers around the world and occasionally in North America have sourced them from countries such as Turkey, Canada, Denmark or the UK. Healthylife uses only FDA-approved generic products, which are subject to the quality and safety evaluation process. Healthylife does not represent or warrant the accuracy of any statements made in the healthylife.ife product's packaging, labeling or manufacturer's information may also contain statement of use and/or potential side effects. Always consult with a qualified healthcare professional before taking any new prescription or over the counter medicines
Enhance treatment effectivenessNorvasc 5mg tablets, also known as amlodipine besylate potassium, are a calcium channel blocker. Amlodipine besylate potassium is a calcium channel blocker that is used to manage and prevent conditions such as:
Norvasc 5mg tablets are not indicated for the treatment of high blood pressure (hypertension) or chest pain. Norvasc 5mg tablets are not indicated for the treatment of angina (chest pain).
Norvasc 5mg tablets are not indicated for the treatment of coronary artery disease. If your doctor decides to start you on Norvasc 5mg tablets and you are not sure, your doctor can adjust your Norvasc 5mg tablets accordingly.
Norvasc 5mg tablets are used to treat high blood pressure (hypertension).
Norvasc 5mg tablets are not indicated for the treatment of hypertension (high blood pressure).
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